Cargando…

Targeting Thymidylate Synthase Enhances the Chemosensitivity of Triple-Negative Breast Cancer Towards 5-FU-Based Combinatorial Therapy

BACKGROUND: The ongoing treatment modalities for breast cancer (BC) primarily rely on the expression status of ER, PR and HER-2 receptors in BC tissues. Our strategy of chemosensitization provides new insights to counter chemoresistance, a major obstacle that limits the benefits of chemotherapy of m...

Descripción completa

Detalles Bibliográficos
Autores principales: Haritha, Nair Hariprasad, Nawab, Akbar, Vijayakurup, Vinod, Anto, Nikhil Ponnoor, Liju, Vijayasteltar B., Alex, Vijai V., Amrutha, Areekkara Nisthul, Aiswarya, Sreekumar U., Swetha, Mundanattu, Vinod, Balachandran S., Sundaram, Sankar, Guijarro, Maria V., Herlevich, Thomas, Krishna, Archana, Nestory, Nesteena K., Bava, Smitha V., Sadasivan, Chittalakkottu, Zajac-Kaye, Maria, Anto, Ruby John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320437/
https://www.ncbi.nlm.nih.gov/pubmed/34336653
http://dx.doi.org/10.3389/fonc.2021.656804