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In vitro prediction of clinical signs of respiratory toxicity in rats following inhalation exposure

To date there are no OECD validated alternative approaches to study toxicity following inhalation exposure to airborne chemicals. The available OECD test guidelines for acute inhalation toxicity aim to estimate a value of the lethal air concentration of the test chemical leading to the death of 50%...

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Detalles Bibliográficos
Autores principales: Da Silva, E., Hickey, C., Ellis, G., Hougaard, K.S., Sørli, J.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320621/
https://www.ncbi.nlm.nih.gov/pubmed/34345862
http://dx.doi.org/10.1016/j.crtox.2021.05.002