Co-culture with mouse embryonic fibroblasts improves maintenance of metabolic function of human small hepatocyte progenitor cells

Derivation and culture of small hepatocyte progenitor cells (SHPCs) capable of proliferating in vitro has been described in rodents and recently in humans. These cells are capable of engrafting in injured livers, however, they display de-differentiated morphology and reduced xenobiotic metabolism ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Sengupta, Srikumar, Johnson, Brian, Seirup, Morten, Ardalani, Hamisha, Duffin, Bret, Barrett-Wilt, Gregory A., Stewart, Ron, Thomson, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320630/
https://www.ncbi.nlm.nih.gov/pubmed/34345838
http://dx.doi.org/10.1016/j.crtox.2020.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320630/
https://www.ncbi.nlm.nih.gov/pubmed/34345838
http://dx.doi.org/10.1016/j.crtox.2020.08.001

Ejemplares similares