Primary hepatocytes isolated from human and porcine donors display similar patterns of cytochrome p450 expression following exposure to prototypical activators of AhR, CAR and PXR

The hepatic cytochrome p450’s (CYP) are of major importance for the metabolism of xenobiotics and knowledge about their regulation is crucial. This knowledge often originates from cell models; primary human hepatocytes (PHH) being the gold standard. However, due to limited availability of high-quali...

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Detalles Bibliográficos
Autores principales: Gerbal-Chaloin, Sabine, Briolotti, Philippe, Daujat-Chavanieu, Martine, Rasmussen, Martin Krøyer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320632/
https://www.ncbi.nlm.nih.gov/pubmed/34345857
http://dx.doi.org/10.1016/j.crtox.2021.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320632/
https://www.ncbi.nlm.nih.gov/pubmed/34345857
http://dx.doi.org/10.1016/j.crtox.2021.03.002

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