Utilizing systems biology to reveal cellular responses to peroxisome proliferator-activated receptor γ ligand exposure

Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor that, upon activation by ligands, heterodimerizes with retinoid X receptor (RXR), binds to PPAR response elements (PPREs), and activates transcription of downstream genes. As PPARγ plays a central role in adipogenesis, fatty...

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Detalles Bibliográficos
Autores principales: Cheng, Vanessa, Reddam, Aalekhya, Bhatia, Anil, Hur, Manhoi, Kirkwood, Jay S., Volz, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320640/
https://www.ncbi.nlm.nih.gov/pubmed/34345858
http://dx.doi.org/10.1016/j.crtox.2021.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320640/
https://www.ncbi.nlm.nih.gov/pubmed/34345858
http://dx.doi.org/10.1016/j.crtox.2021.03.003

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