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Utilizing systems biology to reveal cellular responses to peroxisome proliferator-activated receptor γ ligand exposure

Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor that, upon activation by ligands, heterodimerizes with retinoid X receptor (RXR), binds to PPAR response elements (PPREs), and activates transcription of downstream genes. As PPARγ plays a central role in adipogenesis, fatty...

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Detalles Bibliográficos
Autores principales:	Cheng, Vanessa, Reddam, Aalekhya, Bhatia, Anil, Hur, Manhoi, Kirkwood, Jay S., Volz, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320640/ https://www.ncbi.nlm.nih.gov/pubmed/34345858 http://dx.doi.org/10.1016/j.crtox.2021.03.003

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