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Atractylenolide I Inhibits NLRP3 Inflammasome Activation in Colitis-Associated Colorectal Cancer via Suppressing Drp1-Mediated Mitochondrial Fission

Inflammatory bowel disease (IBD) is an important high-risk factor that promotes the occurrence and development of colon cancer. Research on the mechanism of regulating NLRP3 can provide potential targets for treating NLRP3 inflammasome–related diseases and changing the inflammatory potential of immu...

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Detalles Bibliográficos
Autores principales: Qin, Yao, Yu, Yanwei, Yang, Chendong, Wang, Zhuien, Yang, Yi, Wang, Chongxu, Zheng, Qiusheng, Li, Defang, Xu, Wenjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320763/
https://www.ncbi.nlm.nih.gov/pubmed/34335248
http://dx.doi.org/10.3389/fphar.2021.674340