Cargando…
Atractylenolide I Inhibits NLRP3 Inflammasome Activation in Colitis-Associated Colorectal Cancer via Suppressing Drp1-Mediated Mitochondrial Fission
Inflammatory bowel disease (IBD) is an important high-risk factor that promotes the occurrence and development of colon cancer. Research on the mechanism of regulating NLRP3 can provide potential targets for treating NLRP3 inflammasome–related diseases and changing the inflammatory potential of immu...
Autores principales: | Qin, Yao, Yu, Yanwei, Yang, Chendong, Wang, Zhuien, Yang, Yi, Wang, Chongxu, Zheng, Qiusheng, Li, Defang, Xu, Wenjuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320763/ https://www.ncbi.nlm.nih.gov/pubmed/34335248 http://dx.doi.org/10.3389/fphar.2021.674340 |
Ejemplares similares
-
Norcantharidin combined with Coix seed oil synergistically induces apoptosis and inhibits hepatocellular carcinoma growth by downregulating regulatory T cells accumulation
por: Wang, Dan, et al.
Publicado: (2017) -
Deubiquitinase USP16 induces gouty arthritis via Drp1-dependent mitochondrial fission and NLRP3 inflammasome activation
por: Wang, Qingdong, et al.
Publicado: (2023) -
Metformin Protects Against Diabetes-Induced Cognitive Dysfunction by Inhibiting Mitochondrial Fission Protein DRP1
por: Hu, Yan, et al.
Publicado: (2022) -
Ketogenic Diet Improves Brain Ischemic Tolerance and Inhibits NLRP3 Inflammasome Activation by Preventing Drp1-Mediated Mitochondrial Fission and Endoplasmic Reticulum Stress
por: Guo, Min, et al.
Publicado: (2018) -
Defective mitochondrial fission augments NLRP3 inflammasome activation
por: Park, Sangjun, et al.
Publicado: (2015)