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Facile Synthesis of a Pt(IV) Prodrug of Cisplatin and Its Intrinsically (195m)Pt Labeled Analog: A Step Closer to Cancer Theranostic

BACKGROUND, AIMS AND OBJECTIVES: Cisplatin is extensively used in chemotherapy for treatment of a broad range of cancers. But its undesired side reactions with biomolecules that lead to severe side effects especially on kidney and nervous system, are limiting its clinical utility. To reduce its side...

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Detalles Bibliográficos
Autores principales: Sharma, K. Shitaljit, Vimalnath, K. V., Phadnis, Prasad P., Chakravarty, Rubel, Chakraborty, Sudipta, Dash, Ashutosh, Vatsa, Rajesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320819/
https://www.ncbi.nlm.nih.gov/pubmed/34385784
http://dx.doi.org/10.4103/ijnm.IJNM_188_20