Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors

Background: The Transient Receptor Potential Melastatin member 4 (TRPM4) gene encodes a calcium-activated non-selective cation channel expressed in several tissues. Mutations in TRPM4 have been reported in patients with different types of cardiac conduction defects. It is also linked to immune respo...

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Detalles Bibliográficos
Autores principales: Arullampalam, Prakash, Preti, Barbara, Ross-Kaschitza, Daniela, Lochner, Martin, Rougier, Jean-Sébastien, Abriel, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321095/
https://www.ncbi.nlm.nih.gov/pubmed/34335274
http://dx.doi.org/10.3389/fphar.2021.712354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321095/
https://www.ncbi.nlm.nih.gov/pubmed/34335274
http://dx.doi.org/10.3389/fphar.2021.712354

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