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Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors
Background: The Transient Receptor Potential Melastatin member 4 (TRPM4) gene encodes a calcium-activated non-selective cation channel expressed in several tissues. Mutations in TRPM4 have been reported in patients with different types of cardiac conduction defects. It is also linked to immune respo...
Autores principales: | Arullampalam, Prakash, Preti, Barbara, Ross-Kaschitza, Daniela, Lochner, Martin, Rougier, Jean-Sébastien, Abriel, Hugues |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321095/ https://www.ncbi.nlm.nih.gov/pubmed/34335274 http://dx.doi.org/10.3389/fphar.2021.712354 |
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