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Immune selection suppresses the emergence of drug resistance in malaria parasites but facilitates its spread
Although drug resistance in Plasmodium falciparum typically evolves in regions of low transmission, resistance spreads readily following introduction to regions with a heavier disease burden. This suggests that the origin and the spread of resistance are governed by different processes, and that hig...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321109/ https://www.ncbi.nlm.nih.gov/pubmed/34280179 http://dx.doi.org/10.1371/journal.pcbi.1008577 |