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Immune selection suppresses the emergence of drug resistance in malaria parasites but facilitates its spread

Although drug resistance in Plasmodium falciparum typically evolves in regions of low transmission, resistance spreads readily following introduction to regions with a heavier disease burden. This suggests that the origin and the spread of resistance are governed by different processes, and that hig...

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Detalles Bibliográficos
Autores principales: Whitlock, Alexander O. B., Juliano, Jonathan J., Mideo, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321109/
https://www.ncbi.nlm.nih.gov/pubmed/34280179
http://dx.doi.org/10.1371/journal.pcbi.1008577