Increase of CD4(+)CD25(high)FoxP3(+) cells impairs in vitro human microbicidal activity against Mycobacterium tuberculosis during latent and acute pulmonary tuberculosis

BACKGROUND: Regulatory T cells (Tregs) play a critical role during Mycobacterium tuberculosis (Mtb) infection, modulating host responses while neutralizing excessive inflammation. However, their impact on regulating host protective immunity is not completely understood. Here, we demonstrate that Tre...

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Detalles Bibliográficos
Autores principales: Stringari, Lorenzzo Lyrio, Covre, Luciana Polaco, da Silva, Flávia Dias Coelho, de Oliveira, Vivian Leite, Campana, Maria Carolina, Hadad, David Jamil, Palaci, Moisés, Salgame, Padmini, Dietze, Reynaldo, Gomes, Daniel Cláudio de Oliveira, Ribeiro-Rodrigues, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321116/
https://www.ncbi.nlm.nih.gov/pubmed/34324509
http://dx.doi.org/10.1371/journal.pntd.0009605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321116/
https://www.ncbi.nlm.nih.gov/pubmed/34324509
http://dx.doi.org/10.1371/journal.pntd.0009605

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