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Cell-Type-Specific High Throughput Toxicity Testing in Human Midbrain Organoids

Toxicity testing is a crucial step in the development and approval of chemical compounds for human contact and consumption. However, existing model systems often fall short in their prediction of human toxicity in vivo because they may not sufficiently recapitulate human physiology. The complexity o...

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Detalles Bibliográficos
Autores principales: Renner, Henrik, Becker, Katharina J., Kagermeier, Theresa E., Grabos, Martha, Eliat, Farsam, Günther, Patrick, Schöler, Hans R., Bruder, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321240/
https://www.ncbi.nlm.nih.gov/pubmed/34335182
http://dx.doi.org/10.3389/fnmol.2021.715054