In vitro adaptation and characterization of attenuated hypervariable region 1 swap chimeras of hepatitis C virus

Hepatitis C virus (HCV) chronically infects 70 million people worldwide with an estimated annual disease-related mortality of 400,000. A vaccine could prevent spread of this pervasive human pathogen, but has proven difficult to develop, partly due to neutralizing antibody evasion mechanisms that are...

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Detalles Bibliográficos
Autores principales: Olesen, Christina Holmboe, Augestad, Elias H., Troise, Fulvia, Bukh, Jens, Prentoe, Jannick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321405/
https://www.ncbi.nlm.nih.gov/pubmed/34280245
http://dx.doi.org/10.1371/journal.ppat.1009720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321405/
https://www.ncbi.nlm.nih.gov/pubmed/34280245
http://dx.doi.org/10.1371/journal.ppat.1009720

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