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In vitro adaptation and characterization of attenuated hypervariable region 1 swap chimeras of hepatitis C virus
Hepatitis C virus (HCV) chronically infects 70 million people worldwide with an estimated annual disease-related mortality of 400,000. A vaccine could prevent spread of this pervasive human pathogen, but has proven difficult to develop, partly due to neutralizing antibody evasion mechanisms that are...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321405/ https://www.ncbi.nlm.nih.gov/pubmed/34280245 http://dx.doi.org/10.1371/journal.ppat.1009720 |