Cargando…

From reaction kinetics to dementia: A simple dimer model of Alzheimer’s disease etiology

Oligomers of the amyloid β-protein (Aβ) have been implicated in the pathogenesis of Alzheimer’s disease (AD) through their toxicity towards neurons. Understanding the process of oligomerization may contribute to the development of therapeutic agents, but this has been difficult due to the complexity...

Descripción completa

Detalles Bibliográficos
Autores principales: Lindstrom, Michael R., Chavez, Manuel B., Gross-Sable, Elijah A., Hayden, Eric Y., Teplow, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321409/
https://www.ncbi.nlm.nih.gov/pubmed/34280181
http://dx.doi.org/10.1371/journal.pcbi.1009114