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From reaction kinetics to dementia: A simple dimer model of Alzheimer’s disease etiology
Oligomers of the amyloid β-protein (Aβ) have been implicated in the pathogenesis of Alzheimer’s disease (AD) through their toxicity towards neurons. Understanding the process of oligomerization may contribute to the development of therapeutic agents, but this has been difficult due to the complexity...
Autores principales: | Lindstrom, Michael R., Chavez, Manuel B., Gross-Sable, Elijah A., Hayden, Eric Y., Teplow, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321409/ https://www.ncbi.nlm.nih.gov/pubmed/34280181 http://dx.doi.org/10.1371/journal.pcbi.1009114 |
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