Reverse Plasticity Underlies Rapid Evolution by Clonal Selection within Populations of Fibroblasts Propagated on a Novel Soft Substrate

Mechanical properties such as substrate stiffness are a ubiquitous feature of a cell’s environment. Many types of animal cells exhibit canonical phenotypic plasticity when grown on substrates of differing stiffness, in vitro and in vivo. Whether such plasticity is a multivariate optimum due to hundr...

Descripción completa

Detalles Bibliográficos
Autores principales: Purkayastha, Purboja, Pendyala, Kavya, Saxena, Ayush S, Hakimjavadi, Hesamedin, Chamala, Srikar, Dixit, Purushottam, Baer, Charles F, Lele, Tanmay P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321517/
https://www.ncbi.nlm.nih.gov/pubmed/33871606
http://dx.doi.org/10.1093/molbev/msab102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321517/
https://www.ncbi.nlm.nih.gov/pubmed/33871606
http://dx.doi.org/10.1093/molbev/msab102

Ejemplares similares