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Population Bottlenecks Strongly Affect the Evolutionary Dynamics of Antibiotic Persistence
Bacterial persistence is a potential cause of antibiotic therapy failure. Antibiotic-tolerant persisters originate from phenotypic differentiation within a susceptible population, occurring with a frequency that can be altered by mutations. Recent studies have proven that persistence is a highly evo...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321523/ https://www.ncbi.nlm.nih.gov/pubmed/33871643 http://dx.doi.org/10.1093/molbev/msab107 |