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DNA Breaks-Mediated Fitness Cost Reveals RNase HI as a New Target for Selectively Eliminating Antibiotic-Resistant Bacteria

Antibiotic resistance often generates defects in bacterial growth called fitness cost. Understanding the causes of this cost is of paramount importance, as it is one of the main determinants of the prevalence of resistances upon reducing antibiotics use. Here we show that the fitness costs of antibi...

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Detalles Bibliográficos
Autores principales: Balbontín, Roberto, Frazão, Nelson, Gordo, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321526/
https://www.ncbi.nlm.nih.gov/pubmed/33830249
http://dx.doi.org/10.1093/molbev/msab093