Diverse Molecular Mechanisms Contribute to Differential Expression of Human Duplicated Genes

Emerging evidence links genes within human-specific segmental duplications (HSDs) to traits and diseases unique to our species. Strikingly, despite being nearly identical by sequence (>98.5%), paralogous HSD genes are differentially expressed across human cell and tissue types, though the underly...

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Detalles Bibliográficos
Autores principales: Shew, Colin J, Carmona-Mora, Paulina, Soto, Daniela C, Mastoras, Mira, Roberts, Elizabeth, Rosas, Joseph, Jagannathan, Dhriti, Kaya, Gulhan, O’Geen, Henriette, Dennis, Megan Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Fast Track
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321529/
https://www.ncbi.nlm.nih.gov/pubmed/34009325
http://dx.doi.org/10.1093/molbev/msab131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321529/
https://www.ncbi.nlm.nih.gov/pubmed/34009325
http://dx.doi.org/10.1093/molbev/msab131

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