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Inferring Adaptive Codon Preference to Understand Sources of Selection Shaping Codon Usage Bias

Alternative synonymous codons are often used at unequal frequencies. Classically, studies of such codon usage bias (CUB) attempted to separate the impact of neutral from selective forces by assuming that deviations from a predicted neutral equilibrium capture selection. However, GC-biased gene conve...

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Detalles Bibliográficos
Autores principales: de Oliveira, Janaina Lima, Morales, Atahualpa Castillo, Hurst, Laurence D, Urrutia, Araxi O, Thompson, Christopher R L, Wolf, Jason B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321536/
https://www.ncbi.nlm.nih.gov/pubmed/33871580
http://dx.doi.org/10.1093/molbev/msab099