Cargando…

Exploring a Local Genetic Interaction Network Using Evolutionary Replay Experiments

Understanding how genes interact is a central challenge in biology. Experimental evolution provides a useful, but underutilized, tool for identifying genetic interactions, particularly those that involve non-loss-of-function mutations or mutations in essential genes. We previously identified a stron...

Descripción completa

Detalles Bibliográficos
Autores principales: Vignogna, Ryan C, Buskirk, Sean W, Lang, Gregory I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321538/
https://www.ncbi.nlm.nih.gov/pubmed/33749796
http://dx.doi.org/10.1093/molbev/msab087