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Exploring a Local Genetic Interaction Network Using Evolutionary Replay Experiments
Understanding how genes interact is a central challenge in biology. Experimental evolution provides a useful, but underutilized, tool for identifying genetic interactions, particularly those that involve non-loss-of-function mutations or mutations in essential genes. We previously identified a stron...
Autores principales: | Vignogna, Ryan C, Buskirk, Sean W, Lang, Gregory I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321538/ https://www.ncbi.nlm.nih.gov/pubmed/33749796 http://dx.doi.org/10.1093/molbev/msab087 |
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