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An autoinhibitory clamp of actin assembly constrains and directs synaptic endocytosis

Synaptic membrane-remodeling events such as endocytosis require force-generating actin assembly. The endocytic machinery that regulates these actin and membrane dynamics localizes at high concentrations to large areas of the presynaptic membrane, but actin assembly and productive endocytosis are far...

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Detalles Bibliográficos
Autores principales: Del Signore, Steven J, Kelley, Charlotte F, Messelaar, Emily M, Lemos, Tania, Marchan, Michelle F, Ermanoska, Biljana, Mund, Markus, Fai, Thomas G, Kaksonen, Marko, Rodal, Avital Adah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321554/
https://www.ncbi.nlm.nih.gov/pubmed/34324418
http://dx.doi.org/10.7554/eLife.69597