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Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype

Endothelial-mesenchymal transition (EndMT) is associated with various cardiovascular diseases and in particular with atherosclerosis and plaque instability. However, the molecular pathways that govern EndMT are poorly defined. Specifically, the role of epigenetic factors and histone deacetylases (HD...

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Detalles Bibliográficos
Autores principales: Lecce, Laura, Xu, Yang, V’Gangula, Bhargavi, Chandel, Nirupama, Pothula, Venu, Caudrillier, Axelle, Santini, Maria Paola, d’Escamard, Valentina, Ceholski, Delaine K., Gorski, Przemek A., Ma, Lijiang, Koplev, Simon, Bjørklund, Martin Mæng, Björkegren, Johan L.M., Boehm, Manfred, Bentzon, Jacob Fog, Fuster, Valentin, Kim, Ha Won, Weintraub, Neal L., Baker, Andrew H., Bernstein, Emily, Kovacic, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321575/
https://www.ncbi.nlm.nih.gov/pubmed/34338228
http://dx.doi.org/10.1172/JCI131178