UVB mutagenesis differs in Nras- and Braf-mutant mouse models of melanoma

BRAF-mutant melanomas are more likely than NRAS-mutant melanomas to arise in anatomical locations protected from chronic sun damage. We hypothesized that this discrepancy in tumor location is a consequence of the differential sensitivity of BRAF and NRAS-mutant melanocytes to ultraviolet light (UV)-...

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Detalles Bibliográficos
Autores principales: Bowman, Robert L, Hennessey, Rebecca C, Weiss, Tirzah J, Tallman, David A, Crawford, Emma R, Murphy, Brandon M, Webb, Amy, Zhang, Souhui, La Perle, Krista MD, Burd, Craig J, Levine, Ross L, Shain, A Hunter, Burd, Christin E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321651/
https://www.ncbi.nlm.nih.gov/pubmed/34210801
http://dx.doi.org/10.26508/lsa.202101135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321651/
https://www.ncbi.nlm.nih.gov/pubmed/34210801
http://dx.doi.org/10.26508/lsa.202101135

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