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Functional annotation of noncoding mutations in cancer

In a cancer genome, the noncoding sequence contains the vast majority of somatic mutations. While very few are expected to be cancer drivers, those affecting regulatory elements have the potential to have downstream effects on gene regulation that may contribute to cancer progression. To prioritize...

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Detalles Bibliográficos
Autores principales: Umer, Husen M, Smolinska, Karolina, Komorowski, Jan, Wadelius, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321657/
https://www.ncbi.nlm.nih.gov/pubmed/34282050
http://dx.doi.org/10.26508/lsa.201900523