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In-vitro and in-vivo characterization of CRANAD-2 for multi-spectral optoacoustic tomography and fluorescence imaging of amyloid-beta deposits in Alzheimer mice

The abnormal deposition of fibrillar beta-amyloid (Aβ) deposits in the brain is one of the major histopathological hallmarks of Alzheimer’s disease (AD). Here, we characterized curcumin-derivative CRANAD-2 for multi-spectral optoacoustic tomography and fluorescence imaging of brain Aβ deposits in th...

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Detalles Bibliográficos
Autores principales: Ni, Ruiqing, Villois, Alessia, Dean-Ben, Xose Luis, Chen, Zhenyue, Vaas, Markus, Stavrakis, Stavros, Shi, Gloria, deMello, Andrew, Ran, Chongzhao, Razansky, Daniel, Arosio, Paolo, Klohs, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321919/
https://www.ncbi.nlm.nih.gov/pubmed/34354924
http://dx.doi.org/10.1016/j.pacs.2021.100285