Inclusion complexation of the anticancer drug pomalidomide with cyclodextrins: fast dissolution and improved solubility

Pomalidomide (POM), a potent anticancer thalidomide analogue was characterized in terms of cyclodextrin complexation to improve its aqueous solubility and maintain its anti-angiogenic activity. The most promising cyclodextrin derivatives were selected by phase-solubility studies. From the investigat...

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Detalles Bibliográficos
Autores principales: Szabó, Zoltán-István, Orbán, György, Borbás, Enikő, Csicsák, Dóra, Kádár, Szabina, Fiser, Béla, Dobó, Máté, Horváth, Péter, Kiss, Eszter, Budai, Lívia, Dobos, Judit, Pálla, Tamás, Őrfi, László, Völgyi, Gergely, Tóth, Gergő
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321930/
https://www.ncbi.nlm.nih.gov/pubmed/34355087
http://dx.doi.org/10.1016/j.heliyon.2021.e07581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321930/
https://www.ncbi.nlm.nih.gov/pubmed/34355087
http://dx.doi.org/10.1016/j.heliyon.2021.e07581

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