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Inclusion complexation of the anticancer drug pomalidomide with cyclodextrins: fast dissolution and improved solubility
Pomalidomide (POM), a potent anticancer thalidomide analogue was characterized in terms of cyclodextrin complexation to improve its aqueous solubility and maintain its anti-angiogenic activity. The most promising cyclodextrin derivatives were selected by phase-solubility studies. From the investigat...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321930/ https://www.ncbi.nlm.nih.gov/pubmed/34355087 http://dx.doi.org/10.1016/j.heliyon.2021.e07581 |