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Exercise training mitigates ER stress and UCP2 deficiency-associated coronary vascular dysfunction in atherosclerosis

Endoplasmic reticulum (ER) stress and uncoupling protein-2 (UCP2) activation are opposing modulators of endothelial dysfunction in atherosclerosis. Exercise reduces atherosclerosis plaques and enhances endothelial function. Our aim was to understand how exercise affects ER stress and UCP2 activation...

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Detalles Bibliográficos
Autores principales: Hong, Junyoung, Park, Eunkyung, Lee, Jonghae, Lee, Yang, Rooney, Bridgette V., Park, Yoonjung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322067/
https://www.ncbi.nlm.nih.gov/pubmed/34326395
http://dx.doi.org/10.1038/s41598-021-94944-5