The SUMOylation of TAB2 mediated by TRIM60 inhibits MAPK/NF-κB activation and the innate immune response

Activation of the TAK1 signalosome is crucial for mediating the innate immune response to pathogen invasion and is regulated by multiple layers of posttranslational modifications, including ubiquitination, SUMOylation, and phosphorylation; however, the underlying molecular mechanism is not fully und...

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Detalles Bibliográficos
Autores principales: Gu, Zhiwen, Chen, Xueying, Yang, Wenyong, Qi, Yu, Yu, Hui, Wang, Xiaomeng, Gong, Yanqiu, Chen, Qianqian, Zhong, Bo, Dai, Lunzhi, Qi, Shiqian, Zhang, Zhiqiang, Zhang, Huiyuan, Hu, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322076/
https://www.ncbi.nlm.nih.gov/pubmed/33184450
http://dx.doi.org/10.1038/s41423-020-00564-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322076/
https://www.ncbi.nlm.nih.gov/pubmed/33184450
http://dx.doi.org/10.1038/s41423-020-00564-w

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