Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W

The ubiquitin conjugating enzyme UBE2W catalyzes non-canonical ubiquitination on the N-termini of proteins, although its substrate repertoire remains unclear. To identify endogenous N-terminally-ubiquitinated substrates, we discover four monoclonal antibodies that selectively recognize tryptic pepti...

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Detalles Bibliográficos
Autores principales: Davies, Christopher W., Vidal, Simon E., Phu, Lilian, Sudhamsu, Jawahar, Hinkle, Trent B., Chan Rosenberg, Scott, Schumacher, Frances-Rose, Zeng, Yi Jimmy, Schwerdtfeger, Carsten, Peterson, Andrew S., Lill, Jennie R., Rose, Christopher M., Shaw, Andrey S., Wertz, Ingrid E., Kirkpatrick, Donald S., Koerber, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322077/
https://www.ncbi.nlm.nih.gov/pubmed/34326324
http://dx.doi.org/10.1038/s41467-021-24669-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322077/
https://www.ncbi.nlm.nih.gov/pubmed/34326324
http://dx.doi.org/10.1038/s41467-021-24669-6

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