Torpor enhances synaptic strength and restores memory performance in a mouse model of Alzheimer’s disease

Hibernation induces neurodegeneration-like changes in the brain, which are completely reversed upon arousal. Hibernation-induced plasticity may therefore be of great relevance for the treatment of neurodegenerative diseases, but remains largely unexplored. Here we show that a single torpor and arous...

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Detalles Bibliográficos
Autores principales: de Veij Mestdagh, Christina F., Timmerman, Jaap A., Koopmans, Frank, Paliukhovich, Iryna, Miedema, Suzanne S. M., Goris, Maaike, van der Loo, Rolinka J., Krenning, Guido, Li, Ka Wan, Mansvelder, Huibert D., Smit, August B., Henning, Robert H., van Kesteren, Ronald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322095/
https://www.ncbi.nlm.nih.gov/pubmed/34326412
http://dx.doi.org/10.1038/s41598-021-94992-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322095/
https://www.ncbi.nlm.nih.gov/pubmed/34326412
http://dx.doi.org/10.1038/s41598-021-94992-x

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