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Torpor enhances synaptic strength and restores memory performance in a mouse model of Alzheimer’s disease
Hibernation induces neurodegeneration-like changes in the brain, which are completely reversed upon arousal. Hibernation-induced plasticity may therefore be of great relevance for the treatment of neurodegenerative diseases, but remains largely unexplored. Here we show that a single torpor and arous...
Autores principales: | de Veij Mestdagh, Christina F., Timmerman, Jaap A., Koopmans, Frank, Paliukhovich, Iryna, Miedema, Suzanne S. M., Goris, Maaike, van der Loo, Rolinka J., Krenning, Guido, Li, Ka Wan, Mansvelder, Huibert D., Smit, August B., Henning, Robert H., van Kesteren, Ronald E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322095/ https://www.ncbi.nlm.nih.gov/pubmed/34326412 http://dx.doi.org/10.1038/s41598-021-94992-x |
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