A ratiometric dual luciferase reporter for quantitative monitoring of pre-mRNA splicing efficiency in vivo

Precursor messenger RNA (pre-mRNA) splicing is critical for cell growth and development, and errors in RNA splicing frequently cause cellular dysfunction, abnormal gene expression, and a variety of human diseases. However, there is currently a lack of reliable systems to noninvasively monitor the mR...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Bin, Shi, Xiaorui, Ma, Zhe, Ji, Moxuan, Tang, Chu, Wang, Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Accelerated Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322121/
https://www.ncbi.nlm.nih.gov/pubmed/34216622
http://dx.doi.org/10.1016/j.jbc.2021.100933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322121/
https://www.ncbi.nlm.nih.gov/pubmed/34216622
http://dx.doi.org/10.1016/j.jbc.2021.100933

Ejemplares similares