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A ratiometric dual luciferase reporter for quantitative monitoring of pre-mRNA splicing efficiency in vivo

Precursor messenger RNA (pre-mRNA) splicing is critical for cell growth and development, and errors in RNA splicing frequently cause cellular dysfunction, abnormal gene expression, and a variety of human diseases. However, there is currently a lack of reliable systems to noninvasively monitor the mR...

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Detalles Bibliográficos
Autores principales:	Guo, Bin, Shi, Xiaorui, Ma, Zhe, Ji, Moxuan, Tang, Chu, Wang, Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Accelerated Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322121/ https://www.ncbi.nlm.nih.gov/pubmed/34216622 http://dx.doi.org/10.1016/j.jbc.2021.100933

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