A piggyBac-based platform for genome editing and clonal rhesus macaque iPSC line derivation

Non-human primates (NHPs) are, due to their close phylogenetic relationship to humans, excellent animal models to study clinically relevant mutations. However, the toolbox for the genetic modification of NHPs is less developed than those for other species like mice. Therefore, it is necessary to fur...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodriguez-Polo, Ignacio, Mißbach, Sophie, Petkov, Stoyan, Mattern, Felix, Maierhofer, Anna, Grządzielewska, Iga, Tereshchenko, Yuliia, Urrutia-Cabrera, Daniel, Haaf, Thomas, Dressel, Ralf, Bartels, Iris, Behr, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322147/
https://www.ncbi.nlm.nih.gov/pubmed/34326359
http://dx.doi.org/10.1038/s41598-021-94419-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322147/
https://www.ncbi.nlm.nih.gov/pubmed/34326359
http://dx.doi.org/10.1038/s41598-021-94419-7

Ejemplares similares