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A piggyBac-based platform for genome editing and clonal rhesus macaque iPSC line derivation
Non-human primates (NHPs) are, due to their close phylogenetic relationship to humans, excellent animal models to study clinically relevant mutations. However, the toolbox for the genetic modification of NHPs is less developed than those for other species like mice. Therefore, it is necessary to fur...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322147/ https://www.ncbi.nlm.nih.gov/pubmed/34326359 http://dx.doi.org/10.1038/s41598-021-94419-7 |