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Rational engineering of ratiometric calcium sensors with bright green and red fluorescent proteins

Ratiometric genetically encoded calcium indicators (GECIs) record neural activity with high brightness while mitigating motion-induced artifacts. Recently developed ratiometric GECIs primarily employ cyan and yellow-fluorescent fluorescence resonance energy transfer pairs, and thus fall short in som...

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Detalles Bibliográficos
Autores principales: Zhang, Diming, Redington, Emily, Gong, Yiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322158/
https://www.ncbi.nlm.nih.gov/pubmed/34326458
http://dx.doi.org/10.1038/s42003-021-02452-z