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Rational engineering of ratiometric calcium sensors with bright green and red fluorescent proteins
Ratiometric genetically encoded calcium indicators (GECIs) record neural activity with high brightness while mitigating motion-induced artifacts. Recently developed ratiometric GECIs primarily employ cyan and yellow-fluorescent fluorescence resonance energy transfer pairs, and thus fall short in som...
Autores principales: | Zhang, Diming, Redington, Emily, Gong, Yiyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322158/ https://www.ncbi.nlm.nih.gov/pubmed/34326458 http://dx.doi.org/10.1038/s42003-021-02452-z |
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