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SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts

Hedgehog signaling is essential for bone formation, including functioning as a means for the growth plate to drive skeletal mineralization. However, the mechanisms regulating hedgehog signaling specifically in bone-forming osteoblasts are largely unknown. Here, we identified SLIT and NTRK-like prote...

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Detalles Bibliográficos
Autores principales: Sun, Jun, Shin, Dong Yeon, Eiseman, Mark, Yallowitz, Alisha R., Li, Na, Lalani, Sarfaraz, Li, Zan, Cung, Michelle, Bok, Seoyeon, Debnath, Shawon, Marquez, Sofia Jenia, White, Tommy E., Khan, Abdul G., Lorenz, Ivo C., Shim, Jae-Hyuck, Lee, Francis S., Xu, Ren, Greenblatt, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322311/
https://www.ncbi.nlm.nih.gov/pubmed/34326333
http://dx.doi.org/10.1038/s41467-021-24819-w