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A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein

Increasing evidence suggests the pivotal role of hematopoietic pre-B-cell leukemia transcription factor (PBX)-interacting protein (HPIP/PBXIP1) in cancer development and progression, indicating that HPIP inhibition may be a promising target for cancer therapy. Here, we screened compounds inhibiting...

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Detalles Bibliográficos
Autores principales: Li, Pengyun, Cao, Shengjie, Huang, Yubing, Zhang, Yanan, Liu, Jie, Cai, Xu, Zhou, Lulu, Li, Jianbin, Jiang, Zefei, Ding, Lihua, Zheng, Zhibing, Li, Song, Ye, Qinong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322322/
https://www.ncbi.nlm.nih.gov/pubmed/34326318
http://dx.doi.org/10.1038/s41420-021-00580-3