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FIP200 restricts RNA virus infection by facilitating RIG-I activation

Retinoic acid-inducible gene I (RIG-I) senses viral RNA and instigates an innate immune signaling cascade to induce type I interferon expression. Currently, the regulatory mechanisms controlling RIG-I activation remain to be fully elucidated. Here we show that the FAK family kinase-interacting prote...

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Detalles Bibliográficos
Autores principales: Wang, Lingyan, Song, Kun, Hao, Wenzhuo, Wu, Yakun, Patil, Girish, Hua, Fang, Sun, Yiwen, Huang, Chaoqun, Ritchey, Jerry, Jones, Clinton, Liu, Lin, Guan, Jun-Lin, Li, Shitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322336/
https://www.ncbi.nlm.nih.gov/pubmed/34326461
http://dx.doi.org/10.1038/s42003-021-02450-1