Cargando…

CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice

Male germ cells undergo complex developmental processes eventually producing spermatozoa through spermatogenesis, although the molecular mechanisms remain largely elusive. We have previously identified somatic cell nuclear transfer-reprogramming resistant genes (SRRGs) that are highly enriched for g...

Descripción completa

Detalles Bibliográficos
Autores principales: Akter, Most Sumona, Hada, Masashi, Shikata, Daiki, Watanabe, Gen, Ogura, Atsuo, Matoba, Shogo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322354/
https://www.ncbi.nlm.nih.gov/pubmed/34326397
http://dx.doi.org/10.1038/s41598-021-94851-9