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An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer

Genomic sequencing of thousands of tumors has revealed many genes associated with specific types of cancer. Similarly, large scale CRISPR functional genomics efforts have mapped genes required for cancer cell proliferation or survival in hundreds of cell lines. Despite this, for specific disease sub...

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Detalles Bibliográficos
Autores principales: Das, Rajdeep, Sjöström, Martin, Shrestha, Raunak, Yogodzinski, Christopher, Egusa, Emily A., Chesner, Lisa N., Chen, William S., Chou, Jonathan, Dang, Donna K., Swinderman, Jason T., Ge, Alex, Hua, Junjie T., Kabir, Shaheen, Quigley, David A., Small, Eric J., Ashworth, Alan, Feng, Felix Y., Gilbert, Luke A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322386/
https://www.ncbi.nlm.nih.gov/pubmed/34326322
http://dx.doi.org/10.1038/s41467-021-24919-7