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An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer
Genomic sequencing of thousands of tumors has revealed many genes associated with specific types of cancer. Similarly, large scale CRISPR functional genomics efforts have mapped genes required for cancer cell proliferation or survival in hundreds of cell lines. Despite this, for specific disease sub...
Autores principales: | Das, Rajdeep, Sjöström, Martin, Shrestha, Raunak, Yogodzinski, Christopher, Egusa, Emily A., Chesner, Lisa N., Chen, William S., Chou, Jonathan, Dang, Donna K., Swinderman, Jason T., Ge, Alex, Hua, Junjie T., Kabir, Shaheen, Quigley, David A., Small, Eric J., Ashworth, Alan, Feng, Felix Y., Gilbert, Luke A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322386/ https://www.ncbi.nlm.nih.gov/pubmed/34326322 http://dx.doi.org/10.1038/s41467-021-24919-7 |
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