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Red blood cells contain enzymatically active GPx4 whose abundance anticorrelates with hemolysis during blood bank storage

The antioxidant function of the phospholipid hydroperoxide glutathione peroxidase (GPx4) is vital for the homeostasis of many cell types, from neoplastic cells to normal erythroid precursors. However, some functional proteins in erythroid precursors are lost during the development of red blood cells...

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Detalles Bibliográficos
Autores principales: Stolwijk, Jeffrey M., Stefely, Jonathan A., Veling, Mike T., van ‘t Erve, Thomas J., Wagner, Brett A., Raife, Thomas J., Buettner, Garry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322435/
https://www.ncbi.nlm.nih.gov/pubmed/34298465
http://dx.doi.org/10.1016/j.redox.2021.102073